{"id":1578316,"date":"2022-02-21T15:08:47","date_gmt":"2022-02-21T12:08:47","guid":{"rendered":"https:\/\/www.erzurumflas.com\/?p=1578316"},"modified":"2022-02-21T22:37:17","modified_gmt":"2022-02-21T19:37:17","slug":"japon-bilim-adamlarindan-alzheimer-tedavisinde-umut-olacak-calisma","status":"publish","type":"post","link":"https:\/\/www.erzhaber.com.tr\/?p=1578316","title":{"rendered":"Japon bilim adamlar\u0131ndan Alzheimer tedavisinde umut olacak \u00e7al\u0131\u015fma"},"content":{"rendered":"<header>\n<h3 class=\"summary\">Japon ara\u015ft\u0131rmac\u0131lar, uyar\u0131lm\u0131\u015f pluripotent k\u00f6k h\u00fccrelerden olu\u015fturulan beyin sinir h\u00fccrelerini inceleyerek Alzheimer hastal\u0131\u011f\u0131na yatk\u0131n ki\u015filerin genetik \u00f6zelliklerini belirlemeyi ba\u015fard\u0131.<\/h3>\n<\/header>\n<div class=\"content\">\n<p>Japon bilim adamlar\u0131, hen\u00fcz kesin bir \u00e7aresi bulunmayan Alzheimer hastal\u0131\u011f\u0131n\u0131n tedavisinde umut olabilecek bir \u00e7al\u0131\u015fmaya imza att\u0131. Kyoto \u00dcniversitesi iPS H\u00fccreleri Ara\u015ft\u0131rma ve Uygulama Merkezi&#8217;nden Prof. Haruhisa Inoue liderli\u011findeki ekip, uyar\u0131lm\u0131\u015f pluripotent k\u00f6k h\u00fccrelerden olu\u015fturulan beyin sinir h\u00fccrelerini inceleyerek Alzheimer hastal\u0131\u011f\u0131na yatk\u0131n ki\u015filerin genetik \u00f6zelliklerini belirlemeyi ba\u015fard\u0131.<\/p>\n<div style=\"overflow: auto; position: absolute; height: 0pt; width: 0pt;\">\n<a href=\"http:\/\/www.cokucuzasite.com\/kategori\/manavgat-side-escort\" title=\"manavgat escort\">manavgat escort<\/a><br \/>\n<a href=\"http:\/\/www.cokucuzasite.com\/kategori\/manavgat-side-escort\" title=\"side escort\">side escort<\/a><br \/>\n<a href=\"http:\/\/www.cokucuzasite.com\/kategori\/manavgat-side-escort\" title=\"manavgat  escort bayan\">manavgat escort bayan<\/a>\n<\/div>\n<p>Alzheimer hastal\u0131\u011f\u0131 te\u015fhisi konan 102 ki\u015finin kat\u0131ld\u0131\u011f\u0131 \u00e7al\u0131\u015fmada iPS h\u00fccreleri olarak da bilinen uyar\u0131lm\u0131\u015f pluripotent k\u00f6k h\u00fccreler yoluyla beyin h\u00fccreleri olu\u015fturan ekip, h\u00fccrelerin protein yap\u0131lar\u0131n\u0131 ve genetik durum analizlerini ger\u00e7ekle\u015ftirdi. Alzheimer&#8217;a neden oldu\u011fu d\u00fc\u015f\u00fcn\u00fclen anormal proteinlerle ili\u015fkili 496 k\u00fc\u00e7\u00fck gen mutasyonu belirleyen bilim adamlar\u0131 ayr\u0131ca anormal protein miktar\u0131n\u0131 kontrol eden 8 gen de tespit etti.<\/p>\n<p>\u00c7al\u0131\u015fma sonucunda bulunan genlerin \u00f6zelliklerinin incelenmesinin, Alzheimer hastal\u0131\u011f\u0131n\u0131n kesin nedenin belirlenmesinin, erken te\u015fhis ve yeni tedavi y\u00f6ntemlerinin bulunmas\u0131n\u0131n \u00f6n\u00fcn\u00fc a\u00e7aca\u011f\u0131 \u00f6ng\u00f6r\u00fcl\u00fcyor.<\/p>\n<p><strong>Programlanabilir h\u00fccre<\/strong><\/p>\n<p>Uyar\u0131lm\u0131\u015f pluripotent k\u00f6k h\u00fccreler deri veya kan h\u00fccrelerinden al\u0131n\u0131p, erken olu\u015fum evresinde pluripotent h\u00fccrelere d\u00f6n\u00fc\u015fecek bi\u00e7imde programlanabiliyor. S\u00f6z konusu h\u00fccreler tedavi amac\u0131yla istenen herhangi bir insan h\u00fccresine d\u00f6n\u00fc\u015ft\u00fcr\u00fclebiliyor.<\/p>\n<p><strong>Beyin h\u00fccrelerini yok ediyor<\/strong><\/p>\n<p>Yayg\u0131n g\u00f6r\u00fclen bir demans t\u00fcr\u00fc olup beyin h\u00fccrelerinin yok olmas\u0131na neden olan ilerleyici bir n\u00f6rolojik hastal\u0131k olarak bilinen Alzheimer&#8217;\u0131n d\u00fcnya genelinde yakla\u015f\u0131k 50 milyon ki\u015finin hayat\u0131n\u0131 etkiledi\u011fi biliniyor. D\u00fc\u015f\u00fcnce, haf\u0131za ve davran\u0131\u015f fonksiyonlar\u0131nda azalmaya neden olan Alzheimer&#8217;\u0131n kesin nedeni bilinmezken, etkin bir tedavi y\u00f6ntemi de bulunmuyor.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Japon ara\u015ft\u0131rmac\u0131lar, uyar\u0131lm\u0131\u015f pluripotent k\u00f6k h\u00fccrelerden olu\u015fturulan beyin sinir h\u00fccrelerini inceleyerek Alzheimer hastal\u0131\u011f\u0131na yatk\u0131n ki\u015filerin genetik \u00f6zelliklerini belirlemeyi ba\u015fard\u0131. Japon bilim adamlar\u0131, hen\u00fcz kesin bir \u00e7aresi bulunmayan Alzheimer hastal\u0131\u011f\u0131n\u0131n tedavisinde umut olabilecek bir \u00e7al\u0131\u015fmaya imza att\u0131. Kyoto \u00dcniversitesi iPS H\u00fccreleri Ara\u015ft\u0131rma ve Uygulama Merkezi&#8217;nden Prof. Haruhisa Inoue liderli\u011findeki ekip, uyar\u0131lm\u0131\u015f pluripotent k\u00f6k h\u00fccrelerden olu\u015fturulan beyin [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1578317,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[],"class_list":["post-1578316","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik"],"_links":{"self":[{"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts\/1578316","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1578316"}],"version-history":[{"count":0,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts\/1578316\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/media\/1578317"}],"wp:attachment":[{"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1578316"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1578316"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1578316"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}