Ordu \u00dcniversitesi(OD\u00dc) T\u0131p Fak\u00fcltesi Biyokimya Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Tevfik Noyan, \u00fclke genelinde biyokimya referans de\u011ferlerinin \u00f6l\u00e7\u00fclmesi i\u00e7in uygulanan testlerin tamamland\u0131\u011f\u0131n\u0131 belirterek, “Uluslararas\u0131 kit \u00fcreticilerinin verdi\u011fi de\u011ferlerle bizim buldu\u011fumuz baz\u0131 referans de\u011ferlerinde farkl\u0131l\u0131klar oldu\u011fu ortaya \u00e7\u0131kt\u0131” dedi.<\/p>\n

Uluda\u011f \u00dcniversitesi T\u0131p Fak\u00fcltesi Biyokimya Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Ye\u015fim \u00d6zarda \u00f6nc\u00fcl\u00fc\u011f\u00fcnde ba\u015flat\u0131lan, Uluslararas\u0131 Klinik Kimya ve Laboratuvar T\u0131bbi Cemiyeti Referans Aral\u0131klar\u0131 ve Karar S\u0131n\u0131rlar\u0131 Komitesi ile T\u00fcrk Biyokimya Derne\u011fi taraf\u0131ndan desteklenen “T\u00fcrkiye\u2019de Yayg\u0131n Kullan\u0131lan Biyokimyasal Aral\u0131klar\u0131n Belirlenmesi” \u00e7al\u0131\u015fmas\u0131 2014 y\u0131l\u0131 sonlar\u0131nda tamamland\u0131. Biyokimya testlerinin referans de\u011ferlerini belirlemek amac\u0131yla T\u00fcrkiye\u2019nin 7 farkl\u0131 b\u00f6lgesinde ger\u00e7ekle\u015fen \u00e7ok merkezli \u00e7al\u0131\u015fmaya T\u00fcrkiye genelinde toplam 3 bin 66 sa\u011fl\u0131kl\u0131 yeti\u015fkin birey kat\u0131ld\u0131. 25 biyokimya testinin referans aral\u0131\u011f\u0131n\u0131 belirlenmesi i\u00e7in \u00fclkenin de\u011fi\u015fik \u015fehirlerinden 28 farkl\u0131 laboratuvarda al\u0131nan kan numuneleri toplanarak projenin y\u00fcr\u00fct\u00fcc\u00fcl\u00fc\u011f\u00fcn\u00fc \u00fcstlenen Uluda\u011f \u00dcniversitesi Merkez Laboratuvar\u0131na g\u00f6nderildi. Burada incelenen numunelerin ard\u0131ndan b\u00f6lgeler aras\u0131ndaki biyokimya testlerinin aral\u0131k de\u011ferleri ile uluslararas\u0131 referans aral\u0131klar\u0131n\u0131n de\u011ferlendirilmesi yap\u0131ld\u0131.<\/p>\n

Projenin Ordu ilindeki \u00e7al\u0131\u015fmalar\u0131n\u0131 y\u00fcr\u00fcten Ordu \u00dcniversitesi(OD\u00dc) T\u0131p Fak\u00fcltesi Biyokimya Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Tevfik Noyan, yap\u0131lan ara\u015ft\u0131rmalar sonucunda \u00e7al\u0131\u015fmaya kat\u0131lan b\u00f6lgeler aras\u0131nda biyokimya testlerinin referans aral\u0131k de\u011ferleri aras\u0131nda farkl\u0131l\u0131k olmad\u0131\u011f\u0131n\u0131 tespit ettiklerini s\u00f6yledi. B\u00f6lgeler aras\u0131 de\u011ferlerin e\u015fit oldu\u011funu belirten Noyan, “Yap\u0131lan \u00e7al\u0131\u015fma ile 25 biyokimya testinin referans aral\u0131klar\u0131n\u0131n uluslararas\u0131 kit \u00fcreticilerinin bize \u00f6nermi\u015f olduklar\u0131 referans de\u011ferleri aras\u0131nda bir farkl\u0131l\u0131k olup olmad\u0131\u011f\u0131 ara\u015ft\u0131r\u0131ld\u0131. \u00c7al\u0131\u015fman\u0131n sonucunda \u00f6zellikle lipit parametreleri aras\u0131nda teste tutulan 3 bin 66 ki\u015fin de\u011ferleri g\u00f6z \u00f6n\u00fcne al\u0131nd\u0131\u011f\u0131nda \u00f6ncelikle \u00fclkemizde b\u00f6lgesel a\u00e7\u0131dan referans de\u011ferleri aras\u0131nda bir farkl\u0131l\u0131k olmad\u0131\u011f\u0131 tespit edildi” diye konu\u015ftu.<\/p>\n

T\u00dcRKLER\u0130N BAZI B\u0130YOK\u0130MYA REFERANS DE\u011eERLER\u0130NDE FARKLILIK VAR<\/p>\n

Uluslararas\u0131 kit \u00fcreticilerinin yapt\u0131klar\u0131 referans de\u011ferleri ile T\u00fcrk vatanda\u015flardaki baz\u0131 referans de\u011ferlerinin farkl\u0131l\u0131k g\u00f6sterdi\u011fini ifade eden Noyan, “\u00c7al\u0131\u015fman\u0131n ikinci a\u015famas\u0131nda uluslararas\u0131 ara\u015ft\u0131rmalar\u0131n verdikleri referans de\u011ferleri ile bizim buldu\u011fumuz de\u011ferleri kar\u015f\u0131la\u015ft\u0131rd\u0131\u011f\u0131m\u0131zda halk aras\u0131nda iyi kolesterol ve k\u00f6t\u00fc kolesterol diye isimlendirilen lipit parametreleri a\u00e7\u0131s\u0131ndan \u00f6zellikle dikkat \u00e7eken farkl\u0131l\u0131klar\u0131n oldu\u011fu ortaya \u00e7\u0131kt\u0131. Bunlardan bir tanesi koliner kalp hastal\u0131klar\u0131na kar\u015f\u0131 koruyucu fakt\u00f6r diye bildi\u011fimiz HDL kolesterol seviyesinin referans de\u011ferinin uluslararas\u0131 kit \u00fcreticilerinin \u00f6nermi\u015f oldu\u011fu de\u011fere g\u00f6re daha d\u00fc\u015f\u00fck oldu\u011fu tespit edildi. B\u00f6brek fonksiyonlar\u0131n\u0131n g\u00f6stergesi olan kreatin de\u011ferlerinde ise kit \u00fcreticilerinin \u00f6nerdi\u011fi referans de\u011ferlerine g\u00f6re daha d\u00fc\u015f\u00fck oldu\u011fu belirlendi. Bir di\u011fer farkl\u0131l\u0131k ise total kolesterol, trigliserit ve k\u00f6t\u00fc kolesterol olarak isimlendirdi\u011fimiz LDL ile ili\u015fkiliydi. LDL kolesterol seviyesinin y\u00fcksek olmas\u0131 ise kolenel kalp hastal\u0131klar\u0131na yatk\u0131nl\u0131\u011f\u0131 artt\u0131ran bir fakt\u00f6rd\u00fcr” \u015feklinde konu\u015ftu.<\/p>\n

Ara\u015ft\u0131rman\u0131n sonucunda baz\u0131 enzim seviyelerinde de kit \u00fcreticilerinin belirledi\u011fi referans aral\u0131klar\u0131n\u0131n \u00fczerinde sonu\u00e7lar ortaya \u00e7\u0131kt\u0131\u011f\u0131n\u0131n alt\u0131n\u0131 \u00e7izen Noyan, “\u00c7al\u0131\u015fman\u0131n sonucunda \u00fclkemizde referans de\u011feri olarak trigliserit, total kolesterol ve LDL kolesterol seviyelerinin uluslararas\u0131 kit \u00fcreticilerinin bize \u00f6nermi\u015f oldu\u011fu de\u011fere g\u00f6re daha y\u00fcksek oldu\u011fu tespit edildi. Bunun d\u0131\u015f\u0131nda karaci\u011fer fonksiyonlar\u0131n\u0131 g\u00f6steren alanin amino transferaz(ALT) ve gamma glutamil transferaz(GGT) enzim seviyelerinin y\u00fcksek oldu\u011fu da yap\u0131lan \u00e7al\u0131\u015fmalarda ortaya \u00e7\u0131kt\u0131” ifadelerini kulland\u0131.<\/p>\n

“BEL\u0130RLENEN DE\u011eERLER\u0130N HASTALIKLARIN TANISINDA KULLANILMASINI \u00d6NER\u0130YORUZ”<\/p>\n

7 farkl\u0131 b\u00f6lgede 3 bin 66 ki\u015finin kanlar\u0131 al\u0131narak yap\u0131lan ve ortaya konan test sonu\u00e7lar\u0131 hastal\u0131klar\u0131n tespit edilmesinde kolayl\u0131klar sa\u011flayaca\u011f\u0131n\u0131 vurgulayan Ordu \u00dcniversitesi(OD\u00dc) T\u0131p Fak\u00fcltesi Biyokimya Anabilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Tevfik Noyan, \u015f\u00f6yle konu\u015ftu: “Yap\u0131lan \u00e7al\u0131\u015fma sonucunda varsayaca\u011f\u0131m\u0131z nokta, hastal\u0131klar\u0131n tan\u0131s\u0131n\u0131 de\u011ferlendirirken \u00f6zellikle ulusal bazda elde etti\u011fimiz referans de\u011ferlerini hastal\u0131klar\u0131n tan\u0131s\u0131 i\u00e7in kullan\u0131lmas\u0131n\u0131n daha do\u011fru olaca\u011f\u0131n\u0131 d\u00fc\u015f\u00fcn\u00fcyoruz. Bu sonu\u00e7larla birlikte de\u011ferlendirme yap\u0131l\u0131rken \u00e7al\u0131\u015fmaya kat\u0131lan b\u00f6lgelerde T\u00fcrk insan\u0131n\u0131n \u00f6zellikle kit \u00fcreticilerinin de\u011ferlerine g\u00f6re y\u00fcksek veya d\u00fc\u015f\u00fck buldu\u011fumuz de\u011ferler baz al\u0131n\u0131rsa klinik olarak da tan\u0131 konulmas\u0131nda daha ger\u00e7ek\u00e7i bir yakla\u015f\u0131m olacakt\u0131r.”

\n\t\t\t

\n\t\t\t\tT\u00fcklerin Biyokimya De\u011ferlerinde Farkl\u0131 Sonu\u00e7lar<\/a>\n\t\t\t<\/div><\/figure>\n\t\t<\/div>\n<\/p>\n","protected":false},"excerpt":{"rendered":"

ORDU \u00dcN\u0130VERS\u0130TES\u0130(OD\u00dc) TIP FAK\u00dcLTES\u0130 B\u0130YOK\u0130MYA ANAB\u0130L\u0130M DALI \u00d6\u011eRET\u0130M \u00dcYES\u0130 PROF. DR. TEVF\u0130K NOYAN, \u00dcLKE GENEL\u0130NDE B\u0130YOK\u0130MYA REFERANS DE\u011eERLER\u0130N\u0130N \u00d6L\u00c7\u00dcLMES\u0130 \u0130\u00c7\u0130N UYGULANAN TESTLER\u0130N TAMAMLANDI\u011eINI BEL\u0130RTEREK, “ULUSLARARASI K\u0130T \u00dcRET\u0130C\u0130LER\u0130N\u0130N VERD\u0130\u011e\u0130 DE\u011eERLERLE B\u0130Z\u0130M BULDU\u011eUMUZ BAZI REFERANS DE\u011eERLER\u0130NDE FARKLILIKLAR OLDU\u011eU ORTAYA \u00c7IKTI” DED\u0130.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14,20],"tags":[29865,29866,2407,7380,29864],"class_list":["post-162353","post","type-post","status-publish","format-standard","hentry","category-saglik","category-turkiye","tag-biyokimya","tag-degerlerinde","tag-farkli","tag-sonuclar","tag-tuklerin"],"_links":{"self":[{"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts\/162353","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=162353"}],"version-history":[{"count":0,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts\/162353\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=162353"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=162353"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.erzhaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=162353"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}